Introduction_Online Learning and Teaching, a breakthrough in Higher Education Chapter 0_ The context of Higher Education in Palestine Chapter 1_ Digital Learning Games Scale (DLGS): A scale Development Study Chapter 2_ The Role of an Instructional Design Model Integrating with OER's in Developing Palestinian Teachers' Competencies to Adopt E-learning Chapter 3_ Flipped classroom methodology to support student s' learning during COVID-19 crisis Chapter 4_ Technostress and students' academic productivity: a positive impact Chapter 5_ Comparative Analysis between ADDIE, ASSURE and the Backward Instructional Designs Chapter 6_Online learning and teaching productivity. How to improve metrics in virtual envinroments Chapter 7_Online assessment and e-feedback. The challenge between interaction, behaviour and performance Chapter 8_ Teachers Training and Qualifying. Case study of a PhD programme course, virtualisedChapter 9_ Academic management and university organisation: From face-to-face to fully online in just 2 weeks. Case studyChapter 10_The university strategic plan to face disruptive classes during the COVID-19 pandemic. Case study Chapter 11_ Recommendations based on the presented research. Generic adoption suggestions valid for every institution